Example From Fleiss (1993). The data represent deaths after heart attack in seven different studies where the effect of giving aspirin was investigated. The data are provided in the test workbook in columns marked "Exposed total", "Exposed cases", "Non-exposed total", "Non-exposed cases" and "Study". For this example: Peto odds ratio meta-analysis Stratum Table (xt, xc, nt, nc) 1 49 67 566 557 MRC-1 2 44 64 714 707 CDP 3 102 126 730 724 MRC-2 4 32 38 285 271 GASP 5 85 52 725 354 PARIS 6 246 219 2021 2038 AMIS 7 1570 1720 7017 6880 ISIS-2 Stratum O-E Odds ratio 95% CI Peto weight (V) 1 -8.578692 0.721713 0.492493 1.057619 26.304751 MRC-1 2 -9.540876 0.68386 0.462479 1.011214 25.107478 CDP 3 -10.780024 0.803583 0.607852 1.062341 49.29715 MRC-2 4 -3.447284 0.80134 0.487603 1.316943 15.565457 GASP 5 -6.258224 0.793516 0.544402 1.156621 27.058869 PARIS 6 12.986074 1.132558 0.934809 1.372138 104.323777 AMIS 7 -73.755746 0.895032 0.829531 0.965705 665.092282 ISIS-2 Stratum z P(two sided) 1 -1.672646 P = 0.0944 MRC-1 2 -1.904087 P = 0.0569 CDP 3 -1.535355 P = 0.1247 MRC-2 4 -0.873768 P = 0.3822 GASP 5 -1.203085 P = 0.2289 PARIS 6 1.271412 P = 0.2036 AMIS 7 -2.859927 P = 0.0042 ISIS-2 Pooled odds ratio = 0.896843 (95% CI = 0.840508 to 0.956954) Z (test of odds ratio differs from 1)= -3.289276 P = 0.001 Non-combinability of studies Cochran Q = 9.967823 (df = 6) P = 0.126 IČ (inconsistency) = 39.8% (95% CI = 0% to 73.3%) Here we can say with 95% confidence that the true population odds of death for those who received aspirin after a heart attack from this set of studies is between 0.84 and 0.96 of the same odds for those not receiving aspirin.